This ninety-minute discussion panel will feature department heads and academic faculty who will discuss applying and hiring in academia from both sides of the process, as well as provide insight into an academic career.
Join us for this exciting event to network in the language of your choice! At this multilingual networking event, Dros 21 participants who speak languages other than English have a chance to network and talk about science in their native language or language of choice with other participants. Advanced registration required.
Brenda Andrews (G3: Genes|Genomes|Genetics)
Howard Lipshitz (GENETICS)
Michael Eisen (eLife)
Ondine Cleaver (Developmental Biology)
Swathi Arur (Development)
Mariana Wolfner (GENETICS, PLoS Biology, Fly)
Kelly Ross (Fly)
Pre-post questions you would FlyBase folks to answer here: https://app.sli.do/event/qpvecq9s/live/questions
FlyBase invites all ADRC attendees to come to our virtual booth to learn how to make the best use of FlyBase tools and features for your research and teaching. The 1-hour session will begin at 1:30pm with a 20-minute presentation "What’s New at FlyBase," followed by questions and answers.
Evolution, Immunity, and the Microbiome
Applying to Graduate School and Postdoc Positions
Cell Biology and Growth
Cell Stress and Cell Death
Chromatin, Epigenetics, and Genomics
Disability in Science
Diversity, Equity, and Inclusion
Junctions and Epithelial Dynamics
Doing Science at a PUI
LGBTQ+ in Science
Models of Human Disease
The global pandemic is taking a toll on us all. In our profession, sustained productivity in terms of grants and publications is essential for continued competitiveness with funding and for successful job, promotion, and tenure applications. Yet, many recent studies show that the need to work remotely while fulfilling familial and other obligations during the pandemic is taking a toll on our productivity. Solving the pandemic problem is beyond our capabilities, but there are things each of us can do within our own sphere of influence. This event is to sit down and brainstorm to come up with such activities.
Schedule of Activities
Denise Montell, Duggan Professor and Distinguished Professor, University of California Santa Barbara
Tania Reis, Associate Professor, University of Colorado Anschutz Medical Campus
Jason Tennessen, Associate Professor, Indiana University
Tanya Hoodbhoy, Program Director, National Institute of General Medical Sciences, NIH
Pre-post questions you would FlyBase folks to answer here: https://app.sli.do/event/qpvecq9s/live/questionsFlyBase invites all ADRC attendees to come to our virtual booth to learn how to make the best use of FlyBase tools and features for your research and teaching. The 1-hour session will begin at 1:30pm with a 20-minute presentation "What’s New at FlyBase," followed by questions and answers.
Poster PreviewKaila Gemenes, Genome annotation of Drosophila ananassae dot chromosome contig 33
Neural Circuits and Behavior
Neural Development and Physiology
Parents in Science
Patterning, Morphogenesis, and Organogenesis
Physiology, Metabolism, and Aging
Professional Development and Careers in Science
Regulation of Gene Expression
Reproduction and Gametogenesis
Stem Cells, Regeneration, and Tissue Injury
Teaching at a PUI
Join your colleagues from around the world as we celebrate our community. Although there is no official programming today, all are invited to “gather” together at hashtag #FruitFlyTogether to show the many faces of our world and meaningful ways that we connect to make the fly community.
Today we want to remember those we’ve lost, celebrate our many accomplishments, give a shout of praise for our inspiring colleagues/mentors/trainees, show others who we are, post pictures of our pets and tell everyone what we are doing today. Do you have on a t-shirt from a past Drosophila Conference? What about a shot of you and your labmates? Are you doing something outside of the lab today? Post your pictures on social media and use #Dros21 and #FruitFlyTogether.
3:00pm Tom Neufeld (University of Minnesota, USA)
“Lysosomal pathways: inside & out.”
3:30 pm Hannah Haushild (Simons Lab; University of Heidelberg, Germany)
“The fly ortholog of the Dent’s disease gene CLCN5 is required for endolysosomal
cholesterol and fatty acid extraction.”
3:42 pm Rajan Thakur (O’Connor-Giles lab, Brown University, USA)
“ER-lysosome interactions promote autophagy to regulate synaptic growth.”
3:54 pm Satya Surabhi (Jenny lab; Albert Einstein College of Medicine, USA)
Title: “Addressing the physiological role of endosomal microautophagy.”
4:06 pm Nilay Nandi (Krämer lab; UT Southwestern Medical Center, USA)
“The PPM-type phosphatase Nil regulates a phospho-switch at Acinus-S437A that
controls autophagic responses to Cd2+ exposure and neurodegenerative stress.”
4:18 pm Marco Milan (IRB, Barcelona, Spain)
“Aneuploidy, protein quality control mechanisms and senescence.”
4:30 pm Breakout rooms: identification of pressing questions
4:45 pm Plenum discussion: summary of pressing questions
3:00 pm Greg Reeves, Texas A&M University, Opening Remarks on Systems Developmental Biology
3:10 pm Tomer Stern, Princeton University, Whole embryo single cell mapping of morphogenetic domains during Drosophila gastrulation
3:35 pm Nilay Kumar, University of Notre Dame, Data-driven image analysis and computational modeling approaches of epithelial morphogenesis
4:00 pm David Umulis, Purdue University, A rigorous comparison of BMP-mediated patterning through imaging and simulation reveals distinct mechanisms of gradient formation in zebrafish and Drosophila embryos
4:25 pm Stefano De Renzis, EMBL Heidelberg, Insights from optogenetics: Desensitisation of Notch signalling through dynamic adaptation in the nucleus
4:50 pm Jeremiah Zartman, University of Notre Dame, Concluding Remarks on the Workshop
Brian Oliver, NIDDK, microPublication Fly Science Officer
Thom Kaufman, Indiana University, microPublication Fly Science Officer
Tim Schedl, Washington University School of Medicine, St Louis, microPublication Worm Science Officer
Steven Marygold, Cambridge University/FlyBase
Michael O’Connor, University of Minnesota
Jacob Kagey, University of Detroit Mercy
Laura Reed, University of Alabama
Kai Zinn, California Institute of Technology
Melissa Gilbert-Ross, Emory University
Joyce Stamm, University of Evansville
Kayla Bieser, Nevada State College
Jung-Wan Mok, Korean Advanced Institute of Science and Technology
Session 1. Presentations (10 minutes + 2 min questions each)
3:00 pm Thomas Flatt (Univ. of Fribourg), Josefa González (Institute of Evolutionary Biology, CSIC-UPF), & Paul Schmidt (Univ. of Pennsylvania): The DrosEU and DrosRTEC consortia: an overview
3:12 pm Alan Bergland (Univ. of Virginia) & Martin Kapun (Univ. of Zurich): The DEST dataset: preliminary insights from sequencing >13,000 flies collected around the world
3:24pm Esra Durmaz (Univ. of Fribourg): The DrosEU phenotyping collaboration
3:36pm Josefa González (Institute of Evolutionary Biology, CSIC-UPF): aDaptNATION: a citizen science network in adaptation genomics
3:48pm Daniel Matute (Univ. of North Carolina, Chapel Hill): The dynamics of admixture in African populations of D. melanogaster.
4:00pm Bernard Kim (Stanford University): An open comparative genomic resource of 101 highly contiguous drosophilid genomes
4:12pm Mara Lawniczak (Wellcome Sanger Trust): Malaria transmitting mosquitoes over space and time
4:24pm Megan Wallace (University of Edinburgh): The prevalence and diversity of DNA viruses associated with Drosophila melanogaster in Europe
Session 2. Forum discussion.
4:50 Future consortia efforts. Discussion led by Thomas Flatt, Josefa González, Martin Kapun, Alan Bergland, Paul Schmidt, and Dmitri Petrov.
Session 3. Data workshop
5:30 Data workshop. Answer questions and follow up discussion about data accessibility, browser usage, etc., led by Martin Kapun, Alan Bergland, Jesús Murga, and Marta Coronado-Zamora.
3:00 pm Stanislava Chtarbanova, University of Alabama
3:05 pm Petros Ligoxygakis, Oxford University, Immunity in the fly brain is a key lifespan determinant.
3:30 pm Heather Broihier, Case Western Reserve University, Toll signaling shapes neuron-glia
interactions across lifespan.
3:45 pm David Wassarman, University of Wisconsin-Madison, The innate immune response affects
survival following traumatic brain injury in Drosophila.
4:00 pm Kim McCall, Boston University, Phagocyte-mediated cell death in the Drosophila ovary.
4:15 pm Jason Karpac, Texas A&M University, Exploring the Integration of Nutrient Sensing and Innate
4:30 pm Neal Silverman, University of Massachusetts Medical School
Petros Ligoxygakis, Oxford University
Stanislava Chtarbanova, University of Alabama
Patricia Jumbo-Lucioni, Samford University
Grace Boekhoff-Falk, University of Wisconsin-Madison
Breakout rooms4:50 pm
3:00-3:10: Liqun Luo, HHMI and Department of Biology, Stanford University, Overview of the Fly Cell Atlas: vision, platform, and resources.
3:10-3:20: Vincent Gardeux, EPFL School of Life Sciences (Switzerland), Analyzing, annotating and interpreting Fly Cell Atlas datasets using the Automated Single Cell Analysis Platform: ASAP.
3:20-3:30: Zita Carvalho-Santos, Champalimaud Centre for the Unknown, Lisbon Portugal, Mapping Metabolic Programs in a Whole Animal at Single Cell Resolution.
3:30-3:40: Cameron Berry, Department of Developmental Biology, Stanford University, Differential expression analysis by ASAP of single nuclear sequencing data uncovers novel genes required in testis cyst cells for germ line differentiation.
3:40-3:50: Yifang Liu, Harvard Medical School, Data mining and data analysis of Drosophila scRNA-seq datasets at DRSC.
3:50-3:54: One-minute flash talks:
Julian Dow, University of Glasgow, Single-cell physiology of the Malpighian tubule.
Jessica Velten, Centre for organismal studies Heidelberg (COS), The molecular logic of synaptic wiring.
Nikos Konstantinides, Institut Jacques Monod, Paris, France, A comprehensive series of temporal transcriptions factors in the developing fly visual system.
Ana Veloso, The Berlin Institute for Medical Systems Biology (BIMSB) at Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Neurogenic Lineage Decisions with Single Cell Resolution.
4:00-4:10: Katja Rust, Philipps University Marburg, Germany, An atlas and signaling map of the adult Drosophila ovary.
4:10-4:20: Helen Tauc, Genentech Inc., Investigating changes in transcriptional states of aging Drosophila intestinal stem cell populations.
4:20-4:30: Sara Aibar, VIB-KU Leuven, Tracking chromatin accessibility and enhancer activity at single-cell resolution throughout Drosophila brain development.
4:30-4:40: M. Neset Ozel, New York University, Terminal selector genes link neuronal fate with wiring specificity in the visual system.
4:40-4:50: Anna Alessandra Monaco, BIMSB-MDC, Humboldt Universität zu Berlin, cis-regulatory evolution in Drosophila developmental patterning.
4:50-4:53 One-minute flash talks:
Swann Floc'hlay, Laboratory of Computational Biology, Department of Human Genetics, KU Leuven, Leuven, Belgium, Single-cell regulatory genomics of the wound response program.
Stefano Secchia, European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Heidelberg, Germany, Putting some muscle into the dissection of single cell regulatory landscapes during embryogenesis.
Georg Vogler, Sanford Burnham Prebys Medical Discovery Institute, The Drosophila heart at single cell resolution.
4:53-5:00: Workshop wrap-up / post-workshop social at Gather.town (details provided at the workshop)
3:00 pm Mike Henne, UT Southwestern Medical Center Dallas TX US, Using Drosophila to study organelle crosstalk & the functional diversity of lipid droplets
3:15 pm Raghu Padinjat, National Centre for Biological Sciences-TIFR GKVK Campus, Bangalore India, Localizing biochemical activities to ER-PM contact sites
3:30 pm Patrik Verstreken, VIB Center for Brain & Disease Research KU Leuven Belgium, Sleep dysfunction in Parkinson’s disease
3:45 pm Tao Wang, National Institute of Biological Sciences Beijing China, Mitochondria-ER Lipid Exchange Rebalances PE Homeostasis and maintains neuronal function
4:00 pm Victoria Hewitt, Whitworth Lab, MRC Mitochondrial Biology Unit, University of Cambridge UK, Decreasing pdzd8-mediated mitochondrial-ER contacts in neurons improves fitness by increasing mitophagy
4:15 pm Margret Bülow, University of Bonn, The ER protein Creld controls mitochondrial dynamics and dopaminergic neuron activity
4:30 pm Kai Sun, Center for Metabolic and Degenerative Diseases Institute of Molecular Medicine University of Texas Houston TX US, Regulation of Dynamics of ER-Lipid Droplets by A Novel Factor in Living Cells
4:45 pm Zulfeqhar Syed, Ten Hagen lab, NIH NIDCR Bethesda MD US, Tango1 coordinates ER/Golgi docking sites to mediate the proper packaging of mucin cargo
3:00 pm: Dara Ruiz-Whalen, eCLOSE Institute/Temple University, Community engagement in research: An authentic science experience in Labs@Home.
3:10 pm: Amanda J. Browne*, PPD- Complementary worker of GSK, The importance of role models for student engagement in research.
3:20 pm: Nicole Harrington*, University of Pennsylvania, From student to instructor: The school to science pipeline.
3:30 pm: Christopher Aichele, The Academy at Palumbo High School- School District of Philadelphia, Teaching AP Biology in an underfunded urban setting: Engagement with real data and analysis through eCLOSE Institute's classroom project.
3:40 pm: Ebony Dyson, Abraham Lincoln High School- School District of Philadelphia, A culturally relevant science approach for students and their families.
*Both Amanda and Nicole are awardees of the 2021 Presidential Membership
3:50 pm: Hands on Activity
5 Breakout rooms with 10 participants each. Facilitated by the speakers of this workshop.
4:45 pm: Closing- Dara Ruiz-Whalen
The workshop will cover the molecular genetics, development, neurobiology, genomics, evolution, and population genetics of sexual dimorphism, with an emphasis on cross-disciplinary interactions. Presentations by invited speakers and selected abstracts from each discipline will be followed by moderated discussions. The speakers are encouraged to summarize the key ideas behind their research for people working in other fields, outline the main unsolved questions, offer their opinions about future directions, and suggest connections that could be built with other disciplines.
3:00 PM Opening Remarks
3:05 PM – Stephen F. Goodwin, University of Oxford, A sex-specific switch between visual and olfactory inputs underlies adaptive sex differences in behavior
3:22 PM – Bryson Deanhardt, Duke University, Chromatin based regulation of fru and dsx in courtship circuits with social experience.
3:25 PM – Paula R Roy, University of Utah, It takes two: the behavioral and genetic basis of sexual signal coevolution.
3:35 PM – Lydia Grmai, Johns Hopkins University, Sex-specific ecdysone signaling is established by Dsx to control sexual differentiation in Drosophila gonads.
3:52 PM – Sharvani Mahadevaraju, NIDDK, Sexually dimorphic gonad development and sex-biased expression depends on karyotype (XX or XY), tra (presence or absence) and their interaction.
3:55 PM – Mukulika Ray, Brown University, A sex-specific role for the Drosophila Clamp protein in splicing during early embryonic development.
3:58 PM – Nitin Phadnis, University of Utah, Genomic conflicts and selfish sex chromosomes in Drosophila.
4:15 PM – Samuel Khodursky, The Rockefeller University, Evolution of sex-biased gene expression in the Drosophila brain.
4:18 PM – Peiwei Chen, California Institute of Technology, Adaptation of Drosophila piRNA program to sexually dimorphic TE landscape.
4:28 PM – Ian Dworkin, McMaster University, Sex differences in size and shape, do they reflect the same biological processes? Insights from 350 generations of artificial selection on size, and on sexual size dimorphism in Drosophila melanogaster.
4:45 PM – Caitlin E. McDonough-Goldstein, Syracuse University, Drosophila female reproductive glands contribute to mating plug composition and the timing of sperm ejection.
4:55 PM Q and A
3:00 pm Anna Franz, University College London, Fat cells on the move: motile adipocytes in wound healing.
3:20 pm Bing He, Dartmouth University, A buckling-like mechanism enabled by ectodermal compression facilitates mesoderm invagination in Drosophila.
3:40 pm Kyra Campbell, University of Sheffield, The mechanics of making a midgut.
4:00 pm Jerôme Solon, Basque Foundation for Science, On the control of tissue mechanics during morphogenesis: how to seal epithelial gaps.
4:20 pm Natalie Dye, TU Dresden, Self-organized patterning of cell morphology in the Drosophila wing.
4:40 pm Yanlan Mao, University College London, Coping with mechanical stress – tissue dynamics during development and repair.
Howard Lipshitz (Toronto), Editor in Chief, Genetics
Bernd Pulverer (Heidelberg), Director of Publications, EMBO Press
Kelly Ross (SDSU), Executive Editor, Epigenetics and Commissioning Editor, Fly
Steven Marygold (Cambridge), Group Manager, Flybase