Objective: The invasive fungal infections in hospital is a subject of concern both for the
healthcare professionals .The infection at the hospital is a major risk for the patients the invasive
acts, in first row of morbidity, mortality.
Materials and methods A retrospective study was conducted from september 2013 to Mars
2015, fungal infections immunocompromised patients and the occurrence of Cryptococcus neoformans admitted with Aspergillosis
was diagnosed in 23 individuals. The
median age of the patients under study was39.25 years With male preponderance .(27 cases/36), neck stiffness (16/36), altered
consciousness (14/36), fever (12/36) and convulsions (9/36).Cryptococcal meningitis highly
contributes to mortality in HIV-infected patients. A need exists to improve strategies for clinical
management of AIDS patients and systhematique Aspergillosis 430 samples from different departments .Cryptococcal meningitis in HIV-infected patients is animportant fungal pathogen in immunocompromised patients. High mortality was related to
delayed diagnosis.
Results: prevalence of the meningo-encephalitis cryptococcose at the patients infected by theHIV was 0,4 %. frequency practically decreased while it was 2,09 %Discussion: Theevolution of the
symptomatologie before hospitalization represented 1 week.
disease is progressive,fever, headache,immunosuppressed patient, with a rate of CD4 lower than200 / mm3,
Conclusion: the fungal infection relegated to the last rows neuromeningeal cryptococcose
Aspergillosis in systematic study.