The association between host genotype and the susceptibility to and clinical manifestation of particular pathogens is well-documented, but the particulars of this relationship are rarely understood. A vital first step in better understanding the genetic basis of pathogen susceptibility is analyzing the role of mutation. This study aims to quantify the per-generation input of genetic variance by mutation for susceptibility of Caenorhabditis elegans to Pseudomonas aeruginosa. A set of mutation accumulation (MA) lines, which have undergone 250 generations of single hermaphrodite decent, along with their ancestral parent, were infected with P. aeruginosa. A chain binomial model was then used to estimate the average survival age of all infected individuals. A significant difference was seen in survival probability between ancestral worms and those which had undergone 250 generations of mutation accumulation, with MA worms showing a decreased time until death. We will also report line mean and variance for MA and control lines tested.