Spinal commissural neurons are an attractive model to investigate how multiple guidance cues control growth cone navigation along the dorso-ventral (D-V) and anterior-posterior (A-P) axes by both pre- and post-midline crossing axons. Commissural axons extend toward the floorplate, cross the midline, and turn anteriorly toward the brain. In the zebrafish, the earliest born spinal commissural neuron to navigate the midline and turn rostrally is termed CoPA (Commissural Primary Ascending). We show an evolutionarily conserved role for planar cell polarity (PCP) components as essential for the anterior turning of CoPA axons in the zebrafish spinal cord. Specifically, we show that CoPA axons make randomized turns in fzd3a and vangl2 mutants, with half of CoPA axons executing the correct rostral turn and the other half projecting posteriorly inappropriately. All other guidance decisions along the dorsal-ventral axis are unaltered in PCP mutants. We extend these findings to reveal a role for additional PCP components, celsr3, scribble (scrib,) and protein tyrosine kinase 7 (ptk7), in the anterior guidance of commissural axons. Specifically, we find randomized A-P guidance of CoPA axons in celsr3 morphants, zygotic scrib mutants and maternal-zygotic ptk7 mutants. We observe CoPA axons extend for long distances even after turning the wrong direction in PCP mutants, suggesting that PCP proteins are not required for axon growth per se, but appear to establish a “compass” within the growth cone from which directional pathfinding can be executed. Finally, we show that c-jun-N-terminal kinase (JNK) is an effector of PCP signaling in axon guidance. Embryos treated with the JNK inhibitor, SP600125, from 16-24 hpf, display a similar defect in A-P guidance of CoPA axons as seen in PCP mutants. Taken together, our data establish CoPA commissural axons as a model system to elucidate how planar cell polarity controls axon guidance decisions along the anterior-posterior axis. .