PgmNr E8041: The Effects of Lepidium sativum on Four Tumor Cell Lines.

Authors:
Afnan Felimban


Institutes
Tennessee State University, Nashville, TN.


Abstract:

Cancer is considered as multiple diseases generally because there is not a single treatment for all disease forms. It is important to develop mechanisms to treat cancer that will not harm normal cells and possibly inhibit the reoccurrence of the disease. Natural compounds have been a valuable source for the treatment of human diseases. We are currently studying a medicinal plant to determine its effect on tumor cell lines. The plant is Lepidium sativum.  Methanol extractions from the seeds of this plant produced the secondary compounds use to analyze cell growth. We used AlamarBlue® to measure cell viability. The cancer cell lines testing are breast cancer (BT549), lung cancer (A549), breast cancer (MCF7) and cervical cancer (HeLa). Our analysis shows a significant inhibition of the cancer cells growth after exposure for 24 hour.  These results indicate that Lepidium sativum should be studied more to determine its effect on tumor cells.