|
Wednesday, July 13 |
Date/Time |
Community |
Event |
|
|
|
9:00 am |
- |
12:00 pm |
|
Education Pre-Conference Workshops: | | |
|
|
|
|
Collaborative Hackathon: Make a Lesson Plan Using a Model Organism Card Game Advanced Registration required | | Crystal Ballroom B |
|
|
|
|
Teaching Foundational Concepts through Primary Literature Advanced Registration required | | Crystal Ballroom C |
|
|
|
|
Integrating Discovery-based Research into the Undergraduate Curriculum Advanced Registration required | | Crystal Ballroom D |
|
9:00 am |
- |
4:00 pm |
|
Crash Course in Vision & Change: Learn how to be a more effective educator Advanced Registration required | | Hall of Cities Chicago |
|
1:00 pm |
- |
4:00 pm |
|
Education Pre-Conference Workshops: | | |
|
|
|
|
Collaborative Hackathon: Make a Lesson Plan Using Model Organism Card Game Advanced Registration required | | Crystal Ballroom B |
|
|
|
|
Teaching Foundational Concepts through Primary Literature Advanced Registration required | | Crystal Ballroom C |
|
|
|
|
Integrating Discovery-based Research into the Undergraduate Curriculum Advanced Registration required | | Crystal Ballroom D |
|
2:00 pm |
- |
9:30 pm |
|
Speaker Ready Room Open
| | Hall of Cities Anaheim |
|
2:30 pm |
- |
9:30 pm |
|
Registration Open
| | Cypress Ballroom 1 Alcove |
|
2:30 pm |
- |
9:30 pm |
|
Meal Plan Ticket Desk
| | Cypress Ballroom Registration |
|
5:00 pm |
- |
7:00 pm |
|
Next Stage Mixers
: | | North Tower |
|
|
|
|
Undergrad Mixer Ticketed event | | Key West |
|
|
|
|
Graduate Student Mixer Ticketed event | | Sawgrass/Vinoy |
|
|
|
|
Postdoc Mixer Ticketed event | | Harbor Beach |
|
|
|
|
Early Career Faculty Mixer Ticketed event | | Marco Island |
|
5:00 pm |
- |
12:00 midnight |
|
Family/Nursing Room
| | North Tower Key Largo |
|
7:00 pm |
- |
9:00 pm |
|
Scientific Session(s): | | |
|
|
|
P |
PEQG Keynote 1 Chair: Michael Lynch, Indiana University, Bloomington | | Crystal Ballroom J1, K-L |
|
9:00 pm |
- |
11:00 pm |
|
Opening Mixer with Exhibits
| | Cypress Ballroom |
|
Thursday, July 14 |
Date/Time |
Community |
Event |
|
|
|
12:00 midnight |
- |
12:00 midnight |
|
Posters Open
| | Cypress Ballroom |
|
12:00 midnight |
- |
12:00 midnight |
|
Family/Nursing Room
| | North Tower Key Largo |
|
6:30 am |
- |
1:00 pm |
|
Meal Plan Ticket Desk
| | Cypress Ballroom Registration |
|
7:00 am |
- |
5:00 pm |
|
Registration Open
| | Cypress Ballroom 1 Alcove |
|
7:00 am |
- |
5:00 pm |
|
Speaker Ready Room Open All presenters must upload their presentation 24 hours in advance of their session | | Hall of Cities Anaheim |
|
7:45 am |
- |
10:00 am |
|
Genetics and Determinants of Health Joint Plenary Session Chair: Lynn Cooley, Yale University | | Palms Ballroom Sago/Sabal/Royal |
|
8:00 am |
- |
4:00 pm |
|
Exhibits Open
| | Cypress Ballroom |
|
9:00 am |
- |
8:00 pm |
|
Demo Room: | | |
|
|
|
|
MOD (FlyBase, MGI, SGD, WormBase, Zfin) Demo Room Open for Tutorials and Discussions
FlyBase, MGI, SGD, WormBase, and Zfin invite all Conference registrants to come to the demo room to learn how to make the best use of their tools and features for your research and teaching. Throughout the afternoon, other than the scheduled group presentations noted below, personnel are available in the demo room for one-on-one tutorials, troubleshooting and discussions.
9:00am - 8:00pm Demo room open for tutorials and discussions
Presentations:
12:45-1:00pm FlyBase: "New in FlyBase: Orthology, Human Disease, Gene2Function, miRNA, Author Reagent Form, Protein Domains, Gene Summaries, Video Tutorials, and Community Resources"
1:15-1:30 pm WormBase: "WormBase: a portal to nematode model systems for all research communities"
6:15-6:30 pm SGD: "Saccharomyces Genome Database: New data displays and computational tools"
6:45-7:00 pm MGI: "Searching for human disease, gene expression, genome features on Mouse Genome Informatics"
7:15-7:30 pm Zfin: "Exploring new data at ZFIN: Human disease models and Expression as Phenotype"
| | Palms Ballroom Canary 3-4 |
|
10:30 am |
- |
12:30 pm |
|
Scientific Session(s): | | |
|
|
|
P |
Natural Selection and Adaptation Chair: Dmitri Petrov, Stanford University, CA | | Crystal Ballroom J1, K-L |
|
12:30 pm |
- |
1:30 pm |
|
Mentoring Roundtables #1 Pre-registration Required | | North Tower Harbor Beach/Marco Island |
|
12:30 pm |
- |
1:30 pm |
|
Speaking Up for Genetics and Model Organism Research
| | Crystal Ballroom H |
|
1:30 pm |
- |
3:30 pm |
|
Poster Presentations
| | Cypress Ballroom |
|
1:30 pm |
- |
3:30 pm |
|
GeneticsCareers Center and Job Fair
| | Cypress Ballroom 1C |
|
4:00 pm |
- |
6:00 pm |
|
Scientific Session(s): | | |
|
|
|
P |
James F. Crow Symposium Chair: Bret Payseur, University of Wisconsin | | Crystal Ballroom J1 |
|
|
|
|
Plenary Session and Workshop for Undergraduate Researchers | | Sawgrass |
|
7:45 pm |
- |
9:45 pm |
|
Scientific Session(s): | | |
|
|
|
P |
PEQG Keynote 2 Chair: Lauren McIntyre, University of Florida, Gainesville | | Crystal Ballroom J1, K-L |
|
10:00 pm |
- |
11:30 pm |
|
Science Cafe Event Ticketed event | | Crystal Ballroom H |
|
Friday, July 15 |
Date/Time |
Community |
Event |
|
|
|
12:00 midnight |
- |
12:00 midnight |
|
Posters Open
| | Cypress Ballroom |
|
12:00 midnight |
- |
12:00 midnight |
|
Family/Nursing Room
| | North Tower Key Largo |
|
7:00 am |
- |
5:00 pm |
|
Speaker Ready Room Open All speakers must upload their presentation 24 hours in advance of their session | | Hall of Cities Anaheim |
|
7:30 am |
- |
5:00 pm |
|
Registration Open
| | Cypress Ballroom 1 Alcove |
|
8:00 am |
- |
9:30 am |
|
Scientific Session(s): | | |
|
|
|
P |
Cryptic Variation and Robustness Chair: Bret Payseur, University of Wisconsin, Madison | | Crystal Ballroom J1, K-L |
|
8:00 am |
- |
4:30 pm |
|
Exhibits Open
| | Cypress Ballroom |
|
9:00 am |
- |
8:00 pm |
|
Demo Room: | | |
|
|
|
|
MOD (FlyBase, MGI, SGD, WormBase, Zfin) Demonstrations Open for Tutorials and Discussions
FlyBase, MGI, SGD, WormBase, and Zfin invite all Conference registrants to come to the demo room to learn how to make the best use of their tools and features for your research and teaching. Throughout the afternoon, other than the scheduled group presentations noted below, personnel are available in the demo room for one-on-one tutorials, troubleshooting and discussions.
9:00am - 8:00pm Demo room open for tutorials and discussions
Presentations:
12:45-1:00pm SGD: "Saccharomyces Genome Database: New data displays and computational tools"
1:15-1:30 pm Zfin: "Exploring new data at ZFIN: Human disease models and Expression as Phenotype"
1:40-1:55 pm MGI: "Searching for human disease, gene expression, genome features on Mouse Genome Informatics"
6:45-7:00 pm WormBase: "WormBase: a portal to nematode model systems for all research communities"
7:15-7:30 pm FlyBase: "New in FlyBase: Orthology, Human Disease, Gene2Function, miRNA, Author Reagent Form, Protein Domains, Gene Summaries, Video Tutorials, and Community Resources"
| | Palms Ballroom Canary 3-4 |
|
10:00 am |
- |
12:00 pm |
|
Scientific Session(s): | | |
|
|
|
P |
Mutation & Recombination Chair: Michael Lynch, Indiana University, Bloomington | | Crystal Ballroom J1, K-L |
|
12:00 pm |
- |
1:30 pm |
|
Editor's Panel Discussion and Roundtable Ticketed event | | North Tower Harbor Beach/Marco Island |
|
1:30 pm |
- |
3:30 pm |
|
Poster Presentations
| | Cypress Ballroom |
|
1:30 pm |
- |
3:30 pm |
|
GeneticsCareers Center
| | Cypress Ballroom 1C |
|
2:00 pm |
- |
2:45 pm |
|
GeneticsCareers Workshop - Nailing the Job Talk | | Cypress Ballroom 1B |
|
4:00 pm |
- |
6:00 pm |
|
Scientific Session(s): | | |
|
|
|
P |
Molecular Evolution Chair: Dmitri Petrov, Stanford University, CA | | Crystal Ballroom J1, K-L |
|
6:00 pm |
- |
7:30 pm |
|
Women in Genetics Panel and Networking Ticketed event | | North Tower Harbor Beach/Marco Island |
|
7:30 pm |
- |
9:30 pm |
|
Development and Evolution Joint Plenary Session Chair: Jeannie Lee, Massachusetts Institute of Technology | | Palms Ballroom Sago/Sabal/Royal |
|
Saturday, July 16 |
Date/Time |
Community |
Event |
|
|
|
12:00 midnight |
- |
12:00 pm |
|
Posters Open
| | Cypress Ballroom |
|
12:00 midnight |
- |
12:00 midnight |
|
Family Nursing Room
| | North Tower Key Largo |
|
7:00 am |
- |
5:00 pm |
|
Speaker Ready Room Open All speakers must upload their presentation 24 hours in advance of their session. | | Hall of Cities Anaheim |
|
7:30 am |
- |
2:30 pm |
|
Registration Open
| | Cypress Ballroom 1 Alcove |
|
8:00 am |
- |
10:00 am |
|
Workshops: | | |
|
|
|
|
Automated Tracking for Quantitative Phenotyping Organizers: Andre Brown, Imperial College London; Gordon Berman, Emory University; and Megan Carey, Champalimaud Centre for the Unknown
Advances in sequencing and genome editing have increasingly made phenotyping a bottleneck in genetics. At the same time, imaging technology and computer vision are becoming more accessible, bringing high-throughput quantitative phenotyping to a growing number of labs. At this workshop we will: 1) Share recent advances in animal tracking in a range of model organisms 2) Get feedback from researchers across the communities on what new technologies would be most useful in their work 3) Coordinate efforts and consider working towards a more universal open source animal tracker that can serve as a shared basis for future developments.
Andre Brown, Imperial College London
High-resolution multiworm tracking of C. elegans
Harold Burgess, National Institutes of Health / NICHD Swimming in data: tracking zebrafish through multiple dimensions in space and time
Megan Carey, Champalimaud Centre for the Unknown
LocoMouse: Establishing a quantitative framework for locomotor coordination in mice
Gordon Berman, Emory University
Deciphering the evolution of drosophilid behavior through behavioral embedding
Ben de Bivort, Harvard University
Automated systems for very high-throughput animal tracking
| | Grand Ballroom 3 |
|
|
|
|
CRISPR-based Genome Engineering Organizer: Mike Boxem, Utrecht University, Netherlands
In just a few years' time, CRISPR-based genome engineering has become an essential tool for many C. elegans groups. This exciting technology is still rapidly evolving, with new insights being gained regularly. This workshop offers an opportunity to learn about the latest developments in CRISPR/Cas9 genome engineering, share ideas, and gain practical tips, protocols, and insights to enable the successful application of this technology. In a series of short talks, researchers actively developing novel methods or improvements will present their work, with a focus on practical, technical advice.
Alexandre Paix, HHMI - Johns Hopkins University School of Medicine, Baltimore, MD
Recombineering in C. elegans: genome editing using in vivo assembly of linear DNAs
Matt Schwartz
HHMI - University of Utah, Salt Lake City, UT
SapTrap: High-Throughput Cas9 Gene Modification in C. elegans
Adam Norris
Harvard University, Cambridge, MA
CRISPR-mediated synthetic genetic analysis in C. elegans
Daniel J. Dickinson
Department of Biology and Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC
Genome engineering with the CRISPR/Cas9 system in C. elegans
| | Crystal Ballroom J2 |
|
|
|
|
Using CyVerse Cyberinfrastructure to Enable Data Intensive Research, Collaboration, and Education Organizers: Joslynn Lee, Cold Spring Harbor Laboratory; and Jason Williams, Cold Spring Harbor Laboratory
CyVerse (formerly iPlant Collaborative) is a freely available cyberinfrastructure funded by the National Science Foundation. CyVerse cyberinfrastructure (software, data storage/management, High Performance Computing, and support) enables data-intensive biology by allowing users to analyze and share data efficiently. This workshop will guide attendees through demonstrations of the CyVerse platform and orient them to additional training materials. Demos will introduce data sharing, (meta)data management, resources for genome assembly, annotation, RNA-Seq, variation, and image analysis. CyVerse's mission is to empower discovery at multiple levels, from making bioinformatics applications accessible to the "average bench-biologist" to enabling big-data science that would not otherwise be possible.
| | Grand Ballroom 1 |
|
|
|
|
Model Organisms to Face Environmental Problems Organizers: Cristina Miceli, University of Camerino, Italy; Michael Lynch, Indiana University; and Wei Miao, China Academy of Sciences
In spite of general progress in environmental research, the impact of environmental changes on living organisms and human health remains deeply worrying. Monitoring of water contamination, air pollution, exposure to metals and global climate change can be faced with the contribution of modern omics techniques. This workshop has the objective to gain insight into practical environmental problems by using key model systems in which omics are largely applied. Genomics and transcriptomics are used to identify marker-genes involved in environmental responses, to analyze differential gene expression under environmental stress, to study the relationship between genotype and phenotype, including possible epigenetic control.
Michael Lynch, Indiana University Bloomington, USA, The 5000 Daphnia Genomes Project
Audrey Gash, University of Wisconsin Madison, USA, Application of stress responses in wild yeast to biofuels research
Cristina Miceli/Angela Piersanti, University of Camerino, Italy, Tetrahymena responses to silver nanoparticles
Heather Archer from Patrick Phillips lab, Department of Biology, University of Oregon, USA, High throughput assessment of natural variation in the resistance to starvation stress in C. elegans using microfluidics
Martin Simon, Centre for Human and Molecular Biology, Saarland University, Saarbrücken, Germany, Temperature adaptation and epigenetic control in Paramecium
| | Palms Ballroom Canary 1 |
|
|
|
|
Integrating Research and Teaching: Professional Development for Current and Future Faculty Members Organizers: Rebeccah Kurzhals, Southeast Missouri State University; Joyce Fernandes, Miami University; Pamela Hanson, Birmingham-Southern College; Paula Checchi, Marist College; Gretchen Edwalds-Gilbert, Claremont McKenna, Pitzer, and Scripps Colleges; Eric Stoffregen, Lewis-Clark State College; and Christina Swanson, Arcadia University
This workshop provides current and future faculty (post-docs and graduate students) from different organismal communities with a platform for presenting and discussing strategies to integrate research and pedagogy at the undergraduate level. Goals include: (1) sharing concepts and techniques that encourage integration of model organisms as teaching tools in the classroom and laboratory and (2) networking to promote discussion, collaboration, and support on professional issues associated with balancing the demands of research and teaching.
| | St. Thomas |
|
|
|
|
Informatics Resources to Aid the Genetic Dissection of Neural Circuitry Organizers: David Osumi-Sutherland, European Bioinformatics Institute (EMBL-EBI); Owen Randlett, Harvard University; and Paul Sternberg, Caltech University
With advances in imaging technology and the power of model organism genetics we can now map and functionally dissect entire neural circuits, modulating the activity specific neurons and observing the effects on behavior and circuit function. Researchers need efficient ways to query and visualise data from massive and diverse datasets to identify, understand and target circuit elements. This workshop brings together users and developers of neuroinformatics tools, techniques and resources for Zebrafish, C.elegans and Drosophila. As these communities are working independently to solve similar problems, this workshop provides the opportunity to discuss these problems, share solutions and promote collaboration.
Melissa Haendel (Monarch initiative): Oregon Health & Science University, Portland OR
David Osumi-Sutherland (Virtual Fly Brain): EMBL/EBI, Cambridge UK
Shi Chi-Tin (FlyCircuit): Brain Research Center, National Tsing Hua University, Taiwan
Owen Randlett (Z-Brain): Harvard University, Cambridge MA
Steve Wilson (Zebrafish Brain atlas): University College London, London UK
Paul Sternberg (WormBase): Caltech, Los Angeles, CA
Scott Emmons (WormAtlas): Albert Einstein College of Medicine, New York City NY
| | Palms Ballroom Canary 2 |
|
|
|
|
Everything you Wanted to Know about Sex Organizers: Artyom Kopp, University of California, Davis; Michelle Arbeitman, Florida State University; Mark Siegal , New York University; and Mark Van Doren, Johns Hopkins University
The workshop will cover the molecular genetics, development, neurobiology, genomics, and evolution of sexual dimorphism, with an emphasis on cross-disciplinary interactions. Presentations by 6 invited speakers working in Drosophila, mouse, nematode, zebrafish, and ciliate models will be followed by moderated discussions. The speakers are encouraged to summarize the key ideas behind their research for people working in other models, outline the main unsolved questions, offer their opinions about future directions, and suggest connections that could be built with other models and disciplines.
Yumiko Saga, National Institute of Genetics, Mishima, Japan
Egg or sperm: which is the default?
Bruce W. Draper, Molecular and Cellular Biology, University of California, Davis
Oocyte-produced signals regulate female sex determination and maintenance in zebrafish
Martin J. Cohn, Department of Molecular Genetics & Microbiology, Department of Biology, and UF Genetics Institute, University of Florida
Sexual differentiation of vertebrate external genitalia
Eric S. Haag, Department of Biology, University of Maryland, College Park
Genomic and reproductive consequences of self-fertility in nematodes
Sujal Phadke, J. Craig Venter Institute, La Jolla, CA
Genetic and developmental innovations that govern courtship dynamics in microeukaryotes
Jessica Cande, Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, VA
The Evolution of Courtship Neural Circuits in Drosophila Species
| | Palms Ballroom Sabal |
|
|
|
|
modMetabolome: Model Organism Metabolomics Consortium Workshop Organizers: Laura Reed, University of Alabama; and Arthur Edison, University of Georgia
Metabolomics is emerging as a powerful tool for linking genetic and environmental factors with downstream phenotypes. Model organisms including mouse, zebrafish, yeast, Drosophila, and C. elegans have served as the standard bearers for eukaryotic genomic resource development and comparative genomics. Correspondingly, these organisms are also the logical choices in the field of metabolomics. With coordinated metabolomic analyses across model organism we can elucidate evolutionary conservation and innovation in eukaryotic metabolic networks and improve our understanding of human biology. The "modMetabolome" workshop seeks to promote a broad effort to characterize and curate the metabolomes of model organisms.
| | Grand Ballroom 8A |
|
|
|
|
Feeding Behavior, Nutrition and Metabolism: Emerging Model Organisms Organizers: Tania Reis, University of Colorado; William Ja, The Scripps Research Institute; Supriya Srinivasan, The Scripps Research Institute; and Amnon Schlegel, University of Utah
Caenorhabditis elegans, Drosophila melanogaster and Danio rerio have become powerful models for studying how diet and nutrition influence a wide range of metabolic processes. This workshop will assemble a diverse group of presentations that highlight recent advances in the field of nutrition and metabolism across these genetic model systems. The goal of this workshop is to foster discussions and encourage collaborations among individuals interested in topics ranging from food intake as a fundamental parameter of metabolism to the effects of diet on energy storage and utilization in worms, flies and zebrafish.
Surpriya Srinivasan, The Scripps Research Institute, La Jolla CA
Neural Circuits of Body Fat Control
George Lemieux (Ashrafi Lab), University of California, San Francisco, CA
A central nutrient sensing process coordinates feeding behavior with peripheral metabolism in C. elegans
Maria Carretero (Petrascheck lab), The Scripps Research Institute, La Jolla CA
Study of antipsychotics-induced side effects in C. elegans
Monica Dus, University of Michigan, Ann Harbor, MI
Let them eat cake: Sugar and the brain
Jen Beshel (Zhong Lab), Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
Plus-size model: A neural circuit governing food cue perception and the making of an obese fly
Jason Tennessen, Indiana University, Bloomington, IN
Endogenous L-2-hydroxyglutarate synthesis coordinates aerobic glycolysis with epigenetic modifications in Drosophila
John Rawls, Duke University Medical Center, NC
In vivo imaging reveals growth dynamics of zebrafish adipose tissues during development and nutritional manipulation
Amnon Schlegel, University of Utah School of Medicine, Salt Lake City, UT
FOXN3 Regulates Hepatic Glucose Production
| | Palms Ballroom Royal |
|
|
|
|
Functional Genomics for Conserved Gene Function Discovery Organizers: Stephanie Mohr, Harvard Medical School; Brenda Andrews, University of Toronto; Susan Dutcher, Washington University in St. Louis; Norbert Perrimon, Harvard Medical School; and Yi Zhou, Harvard University
Functional genomics permits gene function discovery at large scale. The power of the approach increases when related genes in multiple species are shown to have similar functions. We bring together experts in functional genomics in single-cell, invertebrate and vertebrate models to present their effective platforms, with an emphasis on cross-species studies (e.g. parallel screens in multiple species or screens in one system followed up in another). Attendees will learn about functional genomics and analysis workflows, and discuss with experts how our communities can collaborate to harness the power of model species for functional genomics screens in new and disease-relevant ways.
Brenda Andrews, University of Toronto
Susan Dutcher, Washington University of St. Louis
Calum MacRae, Brigham and Women's Hospital
Norbert Perrimon, Harvard Medical School
| | Crystal Ballroom J1, K-L |
|
|
|
|
Cell Competition in Flies and Mice Organizers: Erika Bach, New York University Langone Medical Center; Nicholas Baker, Albert Einstein College of Medicine; and Laura Johnston, Columbia University Medical Center
In cell competition, a comparison selects fitter cells during tissue growth and development. Cell competition is relevant to tissue growth, stem cell biology, regeneration and cancer. Studies in Drosophila formalized the concept of context-dependent elimination of ordinarily viable cells and laid the groundwork for mechanistic studies in flies and mice. This workshop will bring together scientists studying cell competition in different tissues and genetic models, including (but not limited to) Drosophila and mouse, to foster communication and promote collaboration. Topics will include signaling mechanisms in diverse contexts, methodologies and the contribution of cell competition to development, aging and disease.
Eugenia Piddini, University of Cambridge, Cambridge, UK
Gines Morata, CSIC-UAM, Madrid, Spain
Tatsushi Igaki, Kyoto University, Kyoto, Japan
Nicholas Baker, Albert Einstein College of Medicine, Bronx, New York, USA
Yasuyuki Fujita, Hokkaido University, Sapporo, Japan
James DeGregori, University of Colorado Anschutz Medical Campus, Aurora, Colorada, USA
Tristan Rodriguez, Imperial College London, London, UK
Miguel Torres, CNIC, Madrid, Spain
| | Crystal Ballroom G1 |
|
|
|
|
Developmental Mechanics Organizers: Rodrigo Fernandez-Gonzalez, University of Toronto; Guy Tanentzapf, University of British Columbia; and Ronen Zaidel-Bar, National University of Singapore
D'Arcy Thompson in his seminal book On growth and form proposed that physical forces play a central role in animal development. Over the last twenty years, the establishment of tools to measure and manipulate mechanical forces in living organisms has demonstrated that mechanical forces influence molecular dynamics and cell behaviors during tissue morphogenesis. We will review the latest advances to visualize and quantify force generation during C. elegans, Drosophila, zebrafish and mouse development, directly targeting four communities that participate in The Allied Genetics Conference. We will discuss recent results demonstrating the interplay between physical forces, molecular dynamics and tissue morphogenesis.
Otger Campas - University of California at Santa Barbara, Santa Barbara, CA
Sevan Hopyan - The Hospital for Sick Children, Toronto, Canada
Karen Kasza - Columbia University, New York, NY
Amy Maddox - University of North Carolina, Chapel Hill, NC
Nicolas Plachta - National University of Singapore
Ronen Zaidel-Bar - National University of Singapore
| | Crystal Ballroom G2 |
|
|
|
|
Model Systems in Drug Discovery Organizer: Daniela Zarnescu, University of Arizona
Recent successes using simple models for drug screening have brought attention to model organisms ranging from yeast to nematodes, to flies and fish as emerging systems that hold great promise for the rapid discovery of high quality therapeutic leads. Talks from expert speakers will focus on the challenges and opportunities of screening for therapeutics in simple model systems. Topics will include screening approaches using various paradigms relevant to human disease. A summary discussion will focus on identifying opportunities and challenges associated with using simple models for drug discovery, and strategies for increasing visibility with funding agencies and pharmaceutical companies.
Daniela Zarnescu, University of Arizona (5 min) - Opening remarks
Stephen Pak, University of Pittsburgh (30 min) - "Drug discovery using C. elegans"
Randall Peterson, Harvard Medical School (30 min) - "Zebrafish behavioral screens identify novel neuroactive compounds"
Ross Cagan, Icahn School of Medicine, Mt Sinai (30 min) - "Mixing Flies, Chemistry, and Supercomputers- A Rational Approach to Cancer Therapeutics"
Workshop participants and audience - Discussion and concluding remarks
| | Grand Ballroom 2 |
|
|
|
|
CRISPR/Cas9 - Techniques and applications in Fish, Flies, & Mice Organizers: Lauryl MJ Nutter, The Centre for Phenogenomics; John Seavitt, Baylor College of Medicine; and Edward Ryder, Wellcome Trust Sanger Institute
This workshop will show participants how CRISPR/Cas9 is being used to enhance discovery using disease model organisms. Speakers will discuss both the technical aspects of producing genetically engineered models with CRISPR/Cas9 as well as the application of those models to particular areas of interest, including undiagnosed diseases and functional genomics. Following the presentations, speakers will be available for a round table discussion with workshop participants and attendees to discuss both technical and applied aspects of the use of CRISPR/Cas9 genome editing in fish, flies and mice.
Moderator: John R. Seavitt, Assistant Professor, Department of Molecular and Human Genetics, Baylor College of Medicine
Shinya Yamamoto, D.V.M., PhD, Department of Molecular & Human Genetics and Program in Developmental Biology, Baylor College of Medicine, CRISPR/Cas9 mutagenesis in Drosophila melanogaster
Hugo J. Bellen, D.V.M., PhD, Investigator, Howard Hughes Medical Institute, Baylor College of Medicine, Human disease allele studies in Drosophila melanogaster
Ann Davidson, PhD, Research Associate, The Hospital for Sick Children Zebrafish Core, Generating zebrafish models of disease using CRISPR-Cas9 mutagenesis
TBN, Zebrafish International Resource Center, University of Oregon, Applications of CRISPR-Cas9 zebrafish
Lauryl MJ Nutter, PhD, Manager, Model Production, The Centre for Phenogenomics, Cas9-RGN: allele design and quality control best practices based on a large sample set
Ed Ryder, PhD, Wellcome Trust Sanger Institute, CRISPR and the 3Rs - optimising workflows and reducing animal numbers in high-throughput mouse production
Jason Heany, PhD, Assistant Professor, Department of Molecular and Human Genetics, Academic Director, Mouse Embryonic Stem Cell Core, Baylor College of Medicine, CRISPR/Cas9 genome editing in mice: Lessons learned from KOMP2
| | Grand Ballroom 7A |
|
|
|
|
Utilizing NCBI Databases for Model Organism Research Organizer: Terence Murphy, NIH
We are experiencing an exponential increase in genomic sequencing data, with profound impacts on research for all model organisms. NCBI provides a variety of resources and services to help access and take advantage of these new datasets. This workshop will cover topics related to data submission to GenBank; genome assembly efforts in mouse and zebrafish by the GRC; and annotation resources in the RefSeq and Gene databases. Annotation examples will focus on zebrafish and mouse genes, but the databases and tools that will be described are applicable to all eukaryotes represented in our databases.
Ilene Mizrachi, NCBI/NLM/NIH -- The 3 W's of Sequence Data Submission: What, Where and When
Valerie Schneider, NCBI/NLM/NIH -- Reference genome assemblies: resources and updates from the GRC
Terence Murphy, NCBI/NLM/NIH - How to annotate for 300 species: the awesome power of NCBI's eukaryotic genome annotation pipeline
Tripti Gupta, NCBI/NLM/NIH -- An introduction to NCBI's RefSeq and Gene resources
Nuala O'Leary, NCBI/NLM/NIH -- Optimizing use of NCBI databases to analyze your favorite gene
| | Grand Ballroom 12-14 |
|
|
|
|
Systems Genetics in Complex Populations Organizers: Martin Ferris, University of North Carolina, Chapel Hill; Fernando Pardo-Manuel de Villena, University of North Carolina, Chapel Hill; and Logan Everett, North Carolina State University
Genetic reference populations are genetically complex, reproducible sets of animals which are derived from >2 parental inbred strains. These populations allow for the integration of population-wide phenotypic, molecular and genetic information across treatments and timescales. Furthermore, these populations are ideal for genetic mapping of complex traits, assessment of genetic perturbation on molecular pathways, and development of new disease models. In this workshop we will familiarize users with mouse (and drosophila) resources useful for these populations; as well as go through experimental design and analysis considerations and approaches for using these systems.
| | Crystal Ballroom A-B |
|
|
|
|
An Introduction to Using Galaxy for Genetic Data Analysis Organizer: Dave Clements, Johns Hopkins University
An essential component of genetics research is extracting information from large and diverse datasets using bioinformatics tools that often require researchers to become proficient in tasks such as Linux package management and system administration. Galaxy is a free open-source data integration and analysis platform that enables researchers to focus on their questions, rather than on the underlying compute infrastructure. After introducing Galaxy the workshop will demonstrate a phenotype and orthology analysis using data from ZFIN, Wormbase, SGD and other databases to discover relationships in multiple datasets from multiple sources.
8:00 A minimal introduction to the Galaxy Project Just enough big picture to give people context; goals of this workshop.
8:10 Introduction to using Galaxy interface basics; importing data, running tools, and managing your workspace.
8:25 The bulk of the workshop will follow an example question from formulation to answer.
9:40 The Galaxy ecosystem and community
9:50 Discussion and Q&A.
| | Grand Ballroom 11 |
|
|
|
|
The InterMOD Consortium: A common interface to model organism data Organizers: Rachel Lyne, University of Cambridge; and Julie Sullivan, University of Cambridge
The budding yeast, rat, zebrafish, nematode, mouse and fruitfly model organism databases (MODs) are developing a new common interface to facilitate gene discovery and analysis, for identification of interactions, disease associations, and pathways, and to build stronger bridges to and from human data. This consortium, working with the open source InterMine project, aims to improve the ease, flexibility and uniformity with which researchers can work integratively with the MOD data, and to do this by means of the nascent NIH "Cloud" Commons Framework. This interactive hands-on workshop will introduce participants to the progress made by this consortium.
Rachel Lyne: Department of Genetics and Cambridge Systems Biology Centre, University of Cambridge, UK
Julie Sullivan: Department of Genetics and Cambridge Systems Biology Centre, University of Cambridge, UK
Sheldon McKay: Ontario Institute for Cancer Research
Jennifer R. Smith, Rat Genome Database (RGD), Medical College of Wisconsin
Kalpana Karra: Saccharomyces Genome Database (SGD), Stanford University
Karen Yook: WormBase, California Institute of Technology
Leyla Ruzicka: ZFIN, Institute of Neuroscience, University of Oregon
Joel Richardson: Mouse Genome Informatics (MGI), The Jackson Laboratory
Karen R. Christie: Mouse Genome Informatics (MGI), The Jackson Laboratory
Andy Schroeder: FlyBase, Harvard University
| | Crystal Ballroom N-Q |
|
8:00 am |
- |
9:00 am |
|
Trainee Bootcamp Workshops: Session 1: | | North Tower |
|
|
|
|
Finding a Job in Academia | | Bahamas |
|
|
|
|
Finding Funding | | Grand Cayman/Puerto Rico |
|
|
|
|
Publishing in the Digital Age | | Aruba |
|
8:00 am |
- |
12:00 pm |
|
Exhibits Open
| | Cypress Ballroom |
|
9:00 am |
- |
10:00 am |
|
Trainee Bootcamp Workshops: Session 2: | | North Tower |
|
|
|
|
Careers Beyond Traditional Academia | | Bahamas |
|
|
|
|
Finding Funding | | Grand Cayman/Puerto Rico |
|
|
|
|
Scientific Publishing | | Aruba |
|
10:00 am |
- |
12:00 pm |
|
Poster Presentations All posters must be removed by 1 pm | | Cypress Ballroom |
|
10:00 am |
- |
12:00 pm |
|
GeneticsCareers Center
| | Cypress Ballroom 1C |
|
10:30 am |
- |
11:15 am |
|
GeneticsCareers Workshop - Negotiating Job Offers | | Cypress Ballroom 1B |
|
12:15 pm |
- |
1:45 pm |
|
Mentoring Roundtables #2 Ticketed event | | North Tower Harbor Beach/Marco Island |
|
1:45 pm |
- |
3:45 pm |
|
Scientific Session(s): | | |
|
|
|
P |
Population Genetics Chair: Lauren McIntyre, University of Florida, Gainesville | | Crystal Ballroom J1, K-L |
|
4:00 pm |
- |
6:00 pm |
|
Scientific Session(s): | | |
|
|
|
P |
Complex Trait Evolution Chair: Dmitri Petrov, Stanford University, CA | | Crystal Ballroom J1, K-L |
|
|
|
|
Spotlight on Undergraduate Research using Genetics Research Models Organizers: Eric Stoffregen, Lewis-Clark State College; Elyse Bolterstein, Northeastern Illinois University; Emily Wiley, Claremont McKenna College; Michelle A. Mondoux, College of the Holy Cross; and Mary Miller, Rhodes College
This workshop will highlight undergraduate research accomplishments from diverse genetics communities . Selected by faculty reviewers, eight student speakers will deliver ten-minute oral presentations. The workshop will illustrate ways that research has become an important part of the college experience through its integration into courses and mentoring in individual research labs.
| | Aruba |
|
|
|
|
You Can Publish That, Too - Publishing Education Resources | | Bahamas |
|
7:25 pm |
- |
7:30 pm |
P |
Announcement of the James F Crow Early Career Researcher Award Recipient
| | Crystal Ballroom J1, K-L |
|
7:30 pm |
- |
9:30 pm |
|
Scientific Session(s): | | |
|
|
|
P |
PEQG Keynote 3 Chair: Bret Payseur, University of Wisconsin, Madison | | Crystal Ballroom J1, K-L |
|
Sunday, July 17 |
Date/Time |
Community |
Event |
|
|
|
12:00 midnight |
- |
12:30 pm |
|
Family/Nursing Room
| | North Tower Key Largo |
|
8:00 am |
- |
10:00 am |
|
Scientific Sessions: | | |
|
|
|
P |
Epistasis Chair: Michael Lynch, Indiana University, Bloomington | | Crystal Ballroom J1, K-L |
|
10:30 am |
- |
12:30 pm |
|
Technology and its Applications Joint Plenary Session Chair: Phil Hieter, University of British Columbia | | Palms Ballroom Sago/Sabal/Royal |
|